HE-RMES (HEritage Research and Methodologies for Equity and Sustainability – Action 1.1.2) is developing an integrated and sustainable model for the protection, conservation, and enhancement of cultural heritage, bringing the solutions initiated in the SAMOTHRACE and CHANGES projects to technological maturity (TRL 7–8). The project operates on five fronts: non-invasive diagnostics and eco-sustainable materials for restoration (WP1); intelligent risk monitoring via IoT networks, edge computing, and generative AI (WP2); a dynamic digital risk atlas for historic landscapes using UAV remote sensing, LiDAR, and GIS (WP3); inclusive accessibility and community participation through adaptive interfaces and social robots (WP4); digital twins applied to complex sites such as Pompeii and Paestum for structural simulations and targeted interventions (WP5). HE-RA (Heritage Empowerment through Regional Alliances – Action 1.1.3b) constitutes the initiative’s widespread innovation hub, structured into eight thematic Work Packages that integrate advanced services for conservation, risk monitoring, diagnostics, accessibility, and sustainable cultural tourism. The Hub aggregates the technologies validated in HE-RMES and transforms them into concrete services for heritage protection agencies, SMEs, and public administrations, promoting technology transfer, patenting, and the creation of new innovative enterprises in the cultural sector of Southern Italy. HE-LIOS (Heritage Empowerment through Learning, Innovation, and Open Systems – Action 1.4.3) is the initiative’s training project, designed to bridge the skills gap between the research system and SMEs active in the digital and green transition of cultural heritage. Organized into four Work Packages, it offers specialized training courses lasting 60–70 hours on enabling technologies (generative AI, IoT, digital twins, non-invasive diagnostics), managerial and entrepreneurial skills, and opportunities for exchange and cooperation among regions and partners. In HE-RMES, EHT is developing SATLab 4 ROOM (Risk mOnitOring of Museum assets), structured in two phases: in the first phase (WP2 – industrial research), it studies and defines conceptual models of anthropogenic risk and computer vision algorithms for the dynamic monitoring of anthropogenic load on indoor and outdoor museum assets, extending the edge computing infrastructure of the Sensors and Algorithms Test Lab already developed in SAMOTHRACE; in the second phase (WP5 – experimental development), it implements and operationally validates the system in real-world scenarios, optimizing the algorithms on edge platforms and producing guidelines for the adoption and scalability of the solution, with a TRL 7 target. In HE-RA, EHT leads scouting and matchmaking activities (ESM-HERA task in WP8 – Communication, Networking, and Territorial Engagement): identifying funders active in digital innovation for cultural heritage, selecting research teams to promote the results, organizing Demo Days, bilateral sessions, and specialized coaching to strengthen pitching and negotiation skills. EHT also participates in WP3 (Services for Risk Monitoring and Mitigation) and WP7 (Strategic Consulting and Technology Transfer), contributing to co-design and collaborative innovation activities for the Cluster. In HE-LIOS, EHT is the WP leader for WP3 (Managerial and Entrepreneurial Upskilling and Reskilling), coordinating the design and delivery of training programs focused on soft skills and entrepreneurial competencies for cultural SMEs: project management, business modeling, cultural heritage marketing, and sustainability. In this role, EHT manages the operational phases—selection of participants, tracking of activities, issuance of certificates—and monitors the training impact through KPIs, questionnaires, and focus groups. EHT also delivers a specialized module on the entrepreneurial exploitation of research—intellectual property, business models, fundraising, pitching, and strategic networking—using an experiential approach based on real-world case studies, individualized mentoring, and pitch simulations.